Data management and a harmonised approach to handle meaningful and comparable data are a key success factor for the assessment of the quality and reliability of methods, as well as for an effective and responsible use of nanomaterials (NMs).

The Investigation/Study/Assay (ISA) tab-delimited (TAB) format (www.isacommons.org) has also been identified as a suitable system for data logging and exchanging of complex metadata concerning nanomaterial. NANoREG has produced a set of easy-to-use 'templates'. The templates have been built by experts in different fields (phys-chem, in vivo and in vitro toxicology) and are aimed at harmonising the logging of experimentally-produced data, and include meaningful and detailed information to support causal correlation analyses, modelling and Safe-by-Design (SbD).
 
Objectives and 'take home messages'
  • NANoREG provides these templates freely to the nanomaterial environmental, health and safety (nanoEHS) community, as jump start towards the harmonisation, sharing and linking of data. This achievement will impact nanoEHS data management at European level, and possibly beyond.
  • The template files are public and free to use and adapt (see license below).
  • Data logging can be an easy task, provided that the right balance between real scientific needs ('need-to-record') and effort put by experimentalists into logging is found.
 
 

Templates for download:

 
 

Phys-Chem:

 

pdfreadme_file.pdf

xlsxbatch_dispersion.xlsx

xlsxcrystalline_phase.xlsx

xlsxdensity.xlsx

xlsxdustiness.xlsx

xlsxElemental_composition_chemical_purity.xlsx

xlsxIEP.xlsx

xlsxlist_of_assays_phys-chem.xlsx

xlsxpotentiometry.xlsx

xlsxsize.xlsx

xlsxsolubility_dissolution_dispersability.xlsx

xlsxsurface_chemistry.xlsx

xlsxVSSA.xlsx

xlsxZetaPotential.xlsx

 

Mammalian toxicology – in vivo:

 

pdfreadme_file.pdf

xlsxaerosol_characterisation.xlsx

xlsxBAL.xlsx

xlsxbiodistribution.xlsx

xlsxbiological_effects_of_inhalation.xlsx

xlsxbiological_effects_of_pulmonary_deposition.xlsx

xlsxenvironmental_toxicity.xlsx

xlsximmunotoxicity.xlsx

xlsxin_vitro_Genotoxicity.xlsx

xlsxlist_of_assays.xlsx

xlsxlong_term_effect_toxicity.xlsx

xlsxorgan_burden.xlsx

xlsxPattern_Distribution_Organs.xlsx

xlsxPBPK.xlsx

 

Mammalian toxicology – in vitro:

 

pdfreadme_file.pdf

xlsxin_vitro_ALI_-_cytotox.xlsx

xlsxin_vitro_barrier_crossing.xlsx

xlsxin_vitro_Cytotoxicity.xlsx

xlsxin_vitro_Genotoxicity.xlsx

xlsxin_vitro_human_cell_transform-hCTA.xlsx

xlsxin_vitro_Immunotox.xlsx

xlsxin_vitro_Viability.xlsx

xlsxlist_of_assays.xlsx

xlsxNM_deposition.xlsx

xlsxOcular_irritation.xlsx