The UK government is proud to support a strong consortium of UK partners who combine world leading cross-disciplinary capability with excellent track records in driving forward regulatory research, risk assessment and standardisation.

The Institute of Occupational Medicine is a UK based leading provider of health and safety solutions, with a wealth of expertise and experience enabling them to provide practical solutions to a broad spectrum of workplace health needs.  The IoM will will play an important role in Work Package 3, developing life cycle understanding of human exposure to nanomaterials.

Leeds University’s Institute of Particle Science and Engineering (IPSE) and NanoManufacturing Institute (NMI) are leading European centres for research into the nanomanufacturing of high value consumer products.   The IPSE and NMI will be contributing to Work Package 5, developing Nano-SAR models to understand nano toxicity and risk.  

Public Health England’s Nanotoxicology Research Centre are participating in Work Package 4 - Biokinetics and toxicity testing in vivo, with specific reference to the biological effects of high aspect ratio nanoparticles (HARN).  PHE will be performing a number of inhalation studies to test hypotheses for grouping/categorisation of HARN.

The National Physical Laboratory is involved with Work Package 5, supporting Leeds University by developing criteria for categorisation and evaluation of datasets for high throughput testing.  NPL are working on the development of solubility testing procedures which go beyond the state of the art.

Heriot Watt University’s School of Life Sciences (www.nano.hw.ac.uk/; www.sls.hw.ac.uk/research/environment/nanomaterials-the-environment.htm; www.sls.hw.ac.uk/research/health/nano-safety-research-group.htm) will be contributing to Work Package 4, specifically developing hypotheses on modes of action of selected nanomaterials and testing OECD guidelines for aquatic species, such as TG225, TG201, TG202, TG211.  HWU’s team is also contributing to Work Package 5, on the advancement of regulatory risk assessment and testing, relating in particular to read-across criteria and high-throughput testing strategies.  HWU are seeking to apply some of the outputs and strategic testing approaches developed through the ITS-NANO Project www.its-nano.eu; www.particleandfibretoxicology.com/content/11/1/9.