Project partners

BASF SE

BASF is the world’s leading chemical company: The Chemical Company. Its portfolio ranges from chemicals, plastics, performance products and crop protection products to oil and gas. We combine economic success with environmental protection and social responsibility. Through science and innovation, we enable our customers in nearly every industry to meet the current and future needs of society. Our products and solutions contribute to conserving resources, ensuring nutrition and improving quality of life. We have summed up this contribution in our corporate purpose: We create chemistry for a sustainable future. BASF had sales of about €74 billion in 2013 and over 112,000 employees as of the end of the year. BASF shares are traded on the stock exchanges in Frankfurt (BAS), London (BFA) and Zurich (AN). Further information on BASF is available on the Internet at www.basf.com.

BASF spent €1.8 billion on research and development in 2013 of which about 80 percent were invested in Europe. On a global scale, more than 10,650 BASF employees are engaged in research and development, approximately 5,300 of whom at BASF SE alone. Our research projects respond both to market requirements (market pull) and to current technological developments (technology push).

BASF has substantial experience in EC-funded research and currently participates in more than 25 projects.

BASF Experimental Toxicology and Ecology Department is one of the leading industrial institutes in the field of regulatory testing of chemicals for hazard identification and risk assessment in the world. GLP was implemented in 1979. BASF has been granted full accreditation by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC). We strictly apply the 3R principle (refinement, reduction, replacement) on animal tests.

BASF SE Carl Bosch Str. 38 D-67056 Ludwigshafen Germany www.basf.com

Federal Institute for Occupational Safety and Health (BAuA)

The Federal Institute for Occupational Safety and Health (BAuA) is a federal governmental research institution and, as a specialist authority, it advises the Federal Ministry of Labour and Social Affairs on a scientific basis in all matters of safety and health at work and of the humane design of work. It conducts, initiates and co-ordinates related research and development (R&D). BAuA analyses the scientific and practical developments in its area of work and concerns itself with the effects of the working conditions on the safety and health of workers in companies and administrative bodies. BAuA develops and tests proposals for preventive occupational safety and health and workplace health promotion. The institute's own research and development activities at the interfaces between science, politics and practice lay the necessary scientific foundation for the qualified performance of sovereign functions, policy advice and the transfer of knowledge and experience to corporate practice. The focal strategic concerns of BAuA's research and development take account of the change in the world of work and the economic and social changes this involves. The federal governmental research institutions (Federal Environmental Agency, Federal Institute for Risk Assessment and BAuA) drew up a joint research strategy in 2007 which describes the need for safety research from the point-of-view of occupational safety and health, environmental protection and consumer protection.  In a focal research element planned as a long-term project over 10 years BAuA intends to contribute to a scientifically based description and evaluation of hitherto inadequately known safety and health risks for workers and to the health and performance-related potentials in the areas of technology mentioned. With a view to research on emerging risks they are focused mainly on the federal government's future for advisory and regulatory needs. The aim is also to have a positive influence at an early stage on the development of the new technologies with a view to a low-risk design of products and the operational introduction of working procedures. Numerous research projects on health matters related to nanotechnology have been launched since 2007.

Federal Institute for Occupational Safety and Health (BAuA) Friedrich-Henkel-Weg 1-25 D-44149 Dortmund Germany www.baua.de/en/Homepage.html

Federal Institute for Risk Assessment (BfR)

The Federal Institute for Risk Assessment was founded in November 2002 under the remit of the Federal Ministry of Food, Agriculture and Consumer Protection (BMELV) to strengthen consumer health protection. "Identify risks - Protect health" - this is the guiding principle for the work of the Federal Institute for Risk Assessment (BfR) in the field of consumer health protection. It is the scientific agency of the Federal Republic of Germany which is responsible for preparing expert reports and opinions on food and feed safety as well as on the safety of substances and consumer products. In this context, the Institute plays an important role in improving consumer protection and food safety. It employs a staff of more than 700. BfR reports to the Federal Ministry of Food, Agriculture and Consumer Protection, the Federal Ministry for the Environment, Nature Conservation and Nuclear Safety (BMU) and to the Federal Ministry of Transport, Building and Urban Affairs. BfR enjoys independence in respect of its scientific assessments and research. The results of its work serve as the basis for scientific advice to the relevant federal ministries and other agencies, for instance the Federal Office of Consumer Protection and Food Safety (BVL) and the Federal Institute for Occupational Safety and Health (BAuA). In its assessments and recommendations BfR is not influenced by any economic, political or social interests. It presents them in such a way that they can be easily understood by the general public.  BfR has the statutory task of engaging in risk communication and enters into an active dialogue with various stakeholders from the sciences, industry, politics, media, associations, non-governmental organisations and consumers. A network of scientific experts who are engaged in the relevant committees provides advice to the Institute on risk assessment issues. BfR is the central, national Focal Point of the European Food Safety Authority (EFSA) and is involved in numerous EU research projects.

Federal Institute for Risk Assessment (BfR) Max-Dohrn-Str. 8-10 D - 10589 Berlin www.bfr.bund.de/en/home.html

University of Leipzig (ULei)

Institute of Medical Physics and Biophysics, the University of Leipzig, has its focus on membranes, nano-engineering and cell biophysics for medical applications. The Institute of Medical Physics and Biophysics is an integrative part of the Medical Faculty and the University Hospital and as such has full access to the facilities of this large life science research unit in the State of Saxony, Germany. The departments of Physics, Chemistry and Biology are in walking distance of the Institute of Medical Physics and Biophysics adjoining the Medical Campus. Dr. Irina Estrela-Lopis and her staff have acquired expert status and experience within Raman imaging and elemental mapping of nanomaterials at the cellular level. The group has a long record of nano-engineering and studying interaction of membranes, lipids, surfactants with non-biological and biological materials by means of various spectroscopic and high resolution techniques. Dr. I. Estrela-Lopis, Prof. E. Donath and their staff have been involved in research projects dealing with nanoparticle toxicity, development of nano-biotechnological devices and testing of nanomaterial-membrane interactions (HINAMOX, EU FP 7)

University of Leipzig Institut for Medical Physics and Biophysics Härtelstraße 16-18 D - 04107 Leipzig www.uni-leipzig.de/~biophys/cms/index.php?id=275

 

Supporting National Partners

As non-consortium members the project is furthermore supported by the Federal Ministry for the Environment, Nature Conservation, Building and Nuclear Safety (www.bmub.bund.de) and by the Federal Environment Agency (www.uba.de). Part of the work is conducted at the Fraunhofer Institute for Toxicology and Experimental Medicine (www.item.fraunhofer.de).

Federal Environment Agency (UBA)

‘For our Environment’ is the mission statement of the Federal Environment Agency (UBA). Founded in 1974, the UBA is Germany’s central federal authority on environmental matters. Its key statutory mandates are: • to provide scientific support to the Federal Government (e.g. the Federal Ministry for the Environment, Nature Conservation, Building and Nuclear Safety; the Federal Ministries for  Health; Research; Transport) • implementation of environmental laws (e.g. emissions trading, authorisation of chemicals, pharmaceuticals, and plant protection agents) • protection of human health against environmental pollutants and health-related environmental monitoring • information of the public about environmental protection Identifying tomorrow’s problems today. The UBA sees itself as an early warning system which detects potential future adverse impacts on mankind and his environment in a timely fashion, assesses associated risks, and offers proposals for practicable solutions. To that end, experts at the Agency carry out research in in-house laboratories in addition to commissioning research projects to scientific institutions in Germany and abroad. UBA acts as partner and Germany’s contact point for many international organizations, including the WHO, UNEP and OECD.The UBA is divided into five divisions and the central division (administration). It has a total staff of around 1500, who work at 13 sites, of which seven are measuring stations of the UBA's own air monitoring network. Some 900 of UBA's total staff work in Dessau-Roßlau.

Umweltbundesamt (UBA) Wörlitzer Platz 1 D-06844 Dessau-Roßlau www.umweltbundesamt.de/en