In NANoREG project, University of Namur (UNamur) is involved in WP2 (Synthesis, supplying and characterization) and WP5 (Advancement of regulatory risk assessment and testing). In WP2, UNamur partner mainly participates to the development of standard operating procedures (SOPs) for nanomaterials (NM) characterization and in the NM dose and fate assessment for regulatory purposes and toxicology.
In WP5, UNamur partner will assess the applicability of solubility testing assays, as used in drug development. UNamur partner will also perform NM transport studies through biological barriers (e.g. intestine epithelium) and will evaluate the toxicity of various NM on different cells (i.e. intestinal Caco-2 cells and human monocytic cell line THP-1) by the analysis of different toxicity markers such as cellular viability and inflammation.